R404A GAS Refrigerant Air conditioning environmental protection HCFC Refrigerant

Ethane, pentafluoro-

Inhalation followed by intravenous injection of epinephrine to simulate stress reactions resulted in cardiac sensitization in dogs. Following repeated inhalation exposure, no adverse effects were observed in rats. No birth defects were noted in the offspring of rats or rabbits exposed by inhalation during pregnancy. No genetic changes were observed in tests using bacteria, animal cells or animals. Single exposure (acute) studies indicate:

Inhalation - Practically Non-toxic to Rats (4-hr LC50 >800,000 ppm)

12 ECOLOGICAL INFORMATION

Ecotoxicological Information

Ethane, 1,1,1-trifluoro-

This material is practically non-toxic to Daphnia magna (48-hr LC50 300 mg/l) and no more than slightly toxic to rainbow trout (96-hr LC50 >40 mg/l).

1,1,1,2-Tetrafluoroethane (HFC-134a)

This material is practically non-toxic to Daphnia magna (48-hr EC50 930 mg/l), rainbow trout (96-hr LC50 450 mg/l) and bacteria (16-hr EC10 >730 mg/l).

Chemical Fate Information

1,1,1,2-Tetrafluoroethane (HFC-134a)

This material is not readily biodegradable (3% after 28-days). Its degradation half-life in the atmosphere is 9.6-16.7 years. The ozone depletion potential (ODP) is 0 and the halocarbon global warming potential (HGWP) is 0.3. It is practically not bioaccumulable (log Pow 1.06).

Ethane, pentafluoro-

When released into the environment, this material is expected to partition almost exclusively into the atmosphere. Based on its low n-octanol/water partition coefficient (log Pow 1.48), bioaccumulation is considered unlikely. In a 28-day ready biodegradability closed bottle test, it appeared to be stable (about 10% degraded). This material does not dissociate in water.

13 DISPOSAL CONSIDERATIONS

Waste Disposal

Recover, reclaim or recycle when practical. Dispose of in accordance with federal, state and local regulations. Note: Chemical additions to, processing of, or otherwise altering this material may make this waste management information incomplete, inaccurate, or otherwise inappropriate. Furthermore, state and local waste disposal requirements may be more restrictive or otherwise different from federal laws and regulations.

14 TRANSPORT INFORMATION

DOT Name Refrigerant Gas R 404A

DOT Technical Name

DOT Hazard Class 2.2

UN Number UN 3337

DOT Packing Group PG NA